MOTS-c 40mg
PreclinicalMitochondrial DNA encoded peptide
Research material. Not for human or animal consumption.
Research overview
MOTS-c 40mg is a lyophilised research peptide supplied in a single vial. MOTS-c is a 16-amino-acid peptide encoded within mitochondrial DNA, first described in 2015. It has been studied mainly in mice and cell models for its role in metabolism, including insulin sensitivity and exercise capacity. A modified analogue of MOTS-c (CB4211) completed early-stage Phase 1a/1b human trials in 2021, but MOTS-c itself has not been tested in published human clinical trials. Store at -20°C away from light, and refrigerate at 2 to 8°C after reconstitution. For research use only. Not for human consumption. Not intended to diagnose, treat, cure or prevent any disease.
Laboratory, computational, ex vivo or animal model research is the main evidence base.
Questions about MOTS-c 40mg
PRODUCT QUESTIONSWhat is MOTS-c 40mg?
MOTS-c 40mg is a lyophilised research peptide supplied in a single vial. It is a 16 amino acid peptide encoded within mitochondrial DNA, first described in 2015.
What research has been published on MOTS-c 40mg?
MOTS-c 40mg contains a peptide studied mainly in mice and cell models for metabolism, insulin sensitivity and exercise capacity. A modified analogue, CB4211, completed Phase 1a/1b human trials in 2021. That analogue is separate from this peptide, which has not been tested in published human clinical trials.
What batch documentation should accompany MOTS-c 40mg?
MOTS-c 40mg: Ask for the COA and analytical reports for the batch being quoted. For this 16 residue peptide, ask for mass spectrometry matching the mitochondrial sequence, HPLC purity with the methionine sulfoxide form reported, and peptide content for the 40mg vial.
How should MOTS-c 40mg storage conditions be assessed?
Store MOTS-c 40mg at −20°C away from light, and refrigerate at 2°C to 8°C after reconstitution. Its N terminal methionine oxidises in air, so keep the vial sealed and limit time open.
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